Research Articles
The Fanconi Anemia Pathway: The Genome's Master Repair Crew
Explore the fascinating world of the Fanconi Anemia pathway, the cellular repair crew that protects our DNA from damage and prevents cancer.
The Double-Edged Sword: How APOBEC3 Enzymes Protect Our Cells Yet Fuel Cancer
Explore the dual role of APOBEC3 cytidine deaminases in DNA break repair and cancer promotion - from antiviral defense to cancer mutagenesis.
The Unlikely Alliance: How a Cellular Duo Safeguards Our Genetic Blueprint
Discover how the Bloom syndrome protein (BLM) and topoisomerase IIIα (TOP3A) work together to prevent genomic instability and protect against cancer.
Cracking the Cellular Code: A Glimpse into the World of A-T Research
Explore the fascinating science behind Ataxia-Telangiectasia (A-T), a rare genetic disorder that reveals our body's DNA repair mechanisms.
The Genome's Unsung Mechanic: How a Cellular 'Origami Master' Fights Cancer
Discover how FKBP25, a nuclear prolyl isomerase, functions as a multifunctional suppressor of genomic instability and its role in DNA repair and cancer prevention.
How a Cancer Gene Hijacks DNA Repair to Drive Treatment Resistance
Discover how the BCR-ABL oncogene promotes mutagenic DNA repair, driving cancer evolution and treatment resistance in chronic myeloid leukemia.
The Cell's Emergency Response: How p53 and BLM Prevent Cancer
Discover how p53 and BLM proteins work together to repair stalled DNA replication forks and prevent cancer through homologous recombination.
The TopBP1 Enigma: How a DNA Repair Protein Fuels Hereditary Breast Cancer
Exploring the dual role of TopBP1 in DNA repair and hereditary breast cancer progression, with insights into therapeutic strategies targeting this critical protein.